The Peptide Reference
The Peptide Reference
References
Best for/Cognition & mood

Cognition & mood

Neurotrophic, neuroprotective and mood-related research.

Ranking reflects how much cited material this reference holds for the goal — how many indications are recorded and how strong the reported effects were. It is a measure of documentation, not a safety or efficacy endorsement, and a compound can rank highly on preclinical work alone.
1
Adamax
Modified heptapeptide derivative

Cognitive Enhancement · Learning and Memory · Neuroplasticity Support · Stroke Recovery · +5 more

9 indications · 4 refs
2
NA Semax Amidate
Modified ACTH analog

Learning Acceleration · Memory Formation · Oxidative Stress Protection · Mental Fatigue Resistance · +4 more

8 indications · 5 refs
3
Semax
ACTH(4-10) synthetic analog

Memory Enhancement · Learning Acceleration · BDNF Upregulation · Neural Connectivity · +5 more

9 indications · 5 refs
4
Dihexa
Modified oligopeptide

Cognitive Recovery · Memory Enhancement · Dendritic Spine Formation · BDNF Upregulation · +5 more

9 indications · 4 refs
5
DSIP
Nonapeptide

Natural Sleep Architecture · Deep Sleep Enhancement · Stress Response Modulation · Sleep Efficiency · +2 more

6 indications · 6 refs
6
Selank
Tuftsin analog

Attention and Focus · Post-Traumatic Stress Disorder · Social Anxiety · Memory Enhancement · +2 more

6 indications · 5 refs
7
Cerebrolysin
Purified porcine brain proteins

Post-Stroke Cognitive Recovery · Acute Stroke · Vascular Dementia · Traumatic Brain Injury · +2 more

6 indications · 5 refs
8
Adalank
Modified heptapeptide

Generalized Anxiety Disorder · Stress-Related Anxiety · Anxiety without Sedation · Cognitive Enhancement · +3 more

7 indications · 0 refs
9
P21
CNTF-derived peptide

Alzheimer's Disease · Neurodegeneration Prevention · Tau Pathology · Neurogenesis · +4 more

8 indications · 0 refs
10
Ara 290
Engineered peptide

Diabetic Neuropathy Treatment · CNS Protection · Peripheral Nerve Regeneration

3 indications · 5 refs
11
FGL
Synthetic peptide derived from the second fibronectin type III module of NCAM

Stroke Recovery · Synaptic Plasticity · Cognitive Decline · Neurogenesis · +2 more

6 indications · 4 refs
12
DNSP-11
GDNF pro-domain derived peptide

Mitochondrial Function · Dopaminergic Neuron Protection · Motivation and Drive · Mood Baseline · +1 more

5 indications · 4 refs
13
IllumiNeuro Protocol
Fixed-ratio peptide combination

Circadian Regulation · Memory & Learning · Focus & Concentration · Neuroprotection · +4 more

8 indications · 0 refs
14
PE-22-28
Linear heptapeptide

Anxiety · Depression · Hippocampal Neurogenesis · Synaptogenesis · +2 more

6 indications · 0 refs
15
NA-Selank Amidate
Modified heptapeptide

Memory Enhancement · Generalized Anxiety · Stress Response · Mood Enhancement · +2 more

6 indications · 0 refs
16
Cyclic Glycine-Proline
Cyclic dipeptide (2,5-diketopiperazine)

Cognitive Enhancement · Neuroprotection · Parkinson's Disease · Alzheimer's Disease

4 indications · 4 refs
17
Epitalon
Tetrapeptide

Pineal Function Restoration · Neurogenesis Support · Retinal Protection

3 indications · 6 refs
18
Pinealon
Tripeptide

Direct CNS Delivery · Traumatic Brain Injury · Cellular Protection · Memory Enhancement · +1 more

5 indications · 0 refs
19
BPC-157
Pentadecapeptide

Peripheral Nerves · Neuroprotection · Spinal Cord Injury

3 indications · 9 refs
20
TB-500
Thymosin fragment

Spinal Cord Injury Support · Brain Health · Neuroprotection

3 indications · 6 refs
21
NAD+
Coenzyme

Cognitive Enhancement · Neuroprotection

2 indications · 6 refs
22
Humanin
Mitochondria-derived peptide

General Neuroprotection · Alzheimer's Disease Protection · Parkinson's Disease Support

3 indications · 0 refs
23
Glutathione
Tripeptide

Parkinson's Disease Support · Neuroprotection

2 indications · 4 refs
24
Cortagen
Tetrapeptide bioregulator

Ischemic Brain Injury Recovery · Nerve Regeneration · Neuroinflammation

3 indications · 0 refs
25
Crystagen
Tripeptide bioregulator

Athletic Immune Support · HSP Expression

2 indications · 0 refs
26
VIP
Neuropeptide

Neuroprotection · Autism Spectrum Disorders · Circadian Rhythm

3 indications · 0 refs
27
Thymulin
Thymic nonapeptide hormone

HPA Axis Modulation · Neuroprotection

2 indications · 0 refs
28
Thymosin Beta-4
Thymosin peptide

Stroke Recovery Enhancement

1 indication · 0 refs