Healing & Recovery

Copper-binding tripeptide, synthetic, aimed at dermal papilla cells and hair follicles. Hair follicles elongate, cells proliferate, VEGF production rises, and TGF-β1 is inhibited. Skin regeneration is supported by way of fibroblast activation and collagen synthesis.

Engineered peptide of 11 amino acids that activates the Innate Repair Receptor (IRR), giving tissue-protective effects while leaving red blood cell production unstimulated. FDA Orphan Drug status applies.

Analog of human relaxin-2 built as a single chain, activating relaxin family peptide receptor 1 (RXFP1) selectively. Where native relaxin-2 depends on two chains, A and B, held together by disulfide bonds in a complex structure, B7-33 achieves the same RXFP1 activation from one simple chain — synthesis is far easier and far cheaper for it. Anti-fibrotic, vasodilatory, and cardioprotective properties are potent in preclinical research, which puts B7-33 forward as a promising therapeutic candidate for heart failure, fibrotic diseases, and vascular dysfunction.

Synthetic peptide taken from a sequence in a gastric juice protein; the literature covers tissue repair, reduced inflammation, and gastrointestinal protection. Described actions are the formation of new blood vessels, increased collagen synthesis, altered growth-factor expression, and protection of tissue against damage, whether delivery is local or systemic.

Copper tripeptide, naturally occurring, present in human plasma, saliva, and urine. It affects 31.2% of human genes, and its level drops significantly with age: roughly 200 ng/ml at age 20 against roughly 80 ng/ml at age 60. Skin regeneration, wound healing, and anti-aging properties are what it is known for.

Polypeptide hormone of 191 amino acids, also called somatropin, with FDA approval covering growth hormone deficiency in children and adults, HIV-associated wasting, and other conditions. Anabolic effects arrive by two routes, direct and indirect through IGF-1.

Synthetic fragment of seven amino acids matching the actin-binding region of thymosin beta-4; equine use was the original application, and the tissue repair properties carried over. It serves as the principal actin-sequestering protein, regulating cell migration, driving angiogenesis, reducing inflammation, and activating stem cell differentiation.

Anabolic bone-building agent with FDA approval, a synthetic analog of parathyroid hormone-related protein (PTHrP). Selective activation of the PTH1 receptor stimulates new bone formation while bone resorption stays minimized. The phase III ACTIVE trial recorded BMD increases at the hip greater than those with teriparatide, alongside substantial reduction in fracture risk. Approval followed in the US in 2017 and the EU in 2022, for postmenopausal women and men with osteoporosis at high fracture risk.

Khavinson bioregulator peptide of four amino acids, out of research on heart tissue. Larger peptides act at the cell surface; Cardiogen instead reaches the cell nucleus, where binding to specific DNA regions regulates gene expression. That epigenetic route supports tissue repair and improves cardiovascular function, with the heart and blood vessels benefiting in particular.

Tripeptide, synthetic, from Professor Vladimir Khavinson. Support for cartilage, connective tissue, and cellular regeneration runs through proliferation markers and modulation of apoptosis pathways.

Synthetic 83-amino acid analog of insulin-like growth factor-1, never approved for human use. An N-terminal extension and the R3 substitution cut interaction with binding proteins, so free circulating levels stay elevated and potency runs about 3x that of native IGF-1.

Tripeptide taken from the C-terminal end of alpha-MSH, potent as an anti-inflammatory. It carries anti-inflammatory and antimicrobial properties but not the pigmentation effects of full α-MSH, which suits it to inflammation management.

IGF-1 splice variant without pegylation, produced locally in muscle tissue after mechanical stress. Its half-life is very short next to PEG-MGF, so administration must be more frequent, or localized by injection.

IGF-1 variant carrying a PEG attachment, which stretches half-life from minutes into hours. Muscle satellite cells are activated after mechanical stress or injury.

Synthetic derivative of thymosin beta-4, made up of the N-terminal acetylated 17–23 amino acid fragment. Within thymosin beta-4 that sequence is the active site behind actin binding, cell migration, and wound healing. Research reports endothelial cell differentiation, angiogenesis, keratinocyte migration, and collagen deposition all promoted, with inflammation decreased. Acetylation guards the N-terminus against degradation and biological activity is retained.

Anabolic bone-building agent with FDA approval, consisting of the first 34 amino acids of parathyroid hormone. Antiresorptive osteoporosis drugs slow bone loss; teriparatide instead stimulates new bone formation actively. Intermittent exposure is the key to the mechanism — continuous PTH drives resorption, whereas daily injections stimulate osteoblasts more than osteoclasts, and net bone formation results. Clinical trials show spine bone density up 8% and vertebral fractures down 65%.

Peptide of 43 amino acids, naturally occurring, central to tissue repair, wound healing, and cellular regeneration. It drives angiogenesis, lowers inflammation, and supports the migration and differentiation of cells.

Khavinson bioregulator tripeptide from Russia's St. Petersburg Institute of Bioregulation and Gerontology. Three amino acids make it up — lysine, glutamic acid, aspartic acid — and its target is the vascular system, protecting blood vessels against age-related decline. Research shows atherosclerosis development limited, endothelial dysfunction decreased, and stem cells activated. As with the other short Khavinson peptides, it reaches the nucleus and influences gene expression.

The one human cathelicidin antimicrobial peptide: 37 amino acids, cationic, derived from hCAP18. Antimicrobial activity is broad-spectrum across bacteria, viruses, and fungi, and immune responses are modulated alongside it.